FREQUENCY OF URINARY TRACT INFECTION AMONG CHILDREN PRESENTING WITH ACUTE GASTROENTERITIS

Authors

  • Muhammad Waqas Khyber Teaching Hospital (KTH), Peshawar, Pakistan. Author
  • Sabahat Amir Khyber Teaching Hospital (KTH), Peshawar, Pakistan. Author
  • Mohammad Edrees Neckzad Khyber Teaching Hospital (KTH), Peshawar, Pakistan. Author
  • Muhammad Ibrahim Khan Khyber Teaching Hospital (KTH), Peshawar, Pakistan. Author
  • Jan Mohammad Khyber Teaching Hospital (KTH), Peshawar, Pakistan. Author
  • Muhammad Ilyas Ghulam Ali Laboratory, Lakki Marwat, Pakistan. Author

DOI:

https://doi.org/10.71000/fpwzrk32

Keywords:

Acute gastroenteritis, Child, Female, , Male, Prevalence, Pediatrics, Urinary tract infections

Abstract

Background: Urinary tract infection (UTI) is the second most common bacterial infection in children and often presents with non-specific symptoms. Acute gastroenteritis (AGE), one of the most frequent causes of pediatric emergency visits, may mask underlying UTIs due to overlapping clinical features, especially in young children. Early detection is critical to prevent renal complications.

Objective: To determine the frequency of urinary tract infection among children presenting with acute gastroenteritis.

Methods: A cross-sectional study was conducted in the Department of Pediatrics, NWGH&RC, over six months. A total of 101 children aged 6 months to 10 years presenting with AGE were enrolled using non-probability consecutive sampling. Midstream urine samples were collected and analyzed through microscopy and culture to diagnose UTI. Data were entered and analyzed using SPSS version 20. Frequencies, means, and post-stratification chi-square tests were applied to determine associations.

Results: The mean age of participants was 62 months. Males made up 51% and females 49% of the study group. UTI was diagnosed in 17 children (16.8%). A higher prevalence was observed among females (18.0%) compared to males (15.4%) and in younger children aged 6–24 months (26.5%). Urban children had a marginally higher UTI rate (18%) than rural children (15%). No statistically significant association was found between UTI and socioeconomic status or residence.

Conclusion: UTI was found to be a relatively frequent comorbidity in children with acute gastroenteritis. Routine screening for UTI in such patients—especially younger children and females—can aid early diagnosis and reduce the risk of renal complications.

Author Biographies

  • Muhammad Waqas, Khyber Teaching Hospital (KTH), Peshawar, Pakistan.

    PGR FCPS Pediatrics, Department of Pediatrics, Khyber Teaching Hospital (KTH), Peshawar, Pakistan.

  • Sabahat Amir, Khyber Teaching Hospital (KTH), Peshawar, Pakistan.

    Professor, Department of Pediatrics, Khyber Teaching Hospital (KTH), Peshawar, Pakistan.

  • Mohammad Edrees Neckzad, Khyber Teaching Hospital (KTH), Peshawar, Pakistan.

    PGR MCPS Pediatrics, Department of Pediatrics, Khyber Teaching Hospital (KTH), Peshawar, Pakistan.

  • Muhammad Ibrahim Khan, Khyber Teaching Hospital (KTH), Peshawar, Pakistan.

    PGR FCPS Pediatrics, Department of Pediatrics, Khyber Teaching Hospital (KTH), Peshawar, Pakistan.

  • Jan Mohammad, Khyber Teaching Hospital (KTH), Peshawar, Pakistan.

    Professor, Department of Pediatrics, Khyber Teaching Hospital (KTH), Peshawar, Pakistan.

  • Muhammad Ilyas, Ghulam Ali Laboratory, Lakki Marwat, Pakistan.

    Diploma in Pathology, Ghulam Ali Laboratory, Lakki Marwat, Pakistan.

References

Rethi S, Kairam N, Amato CS, Allegra JR, Eskin B. Six Diagnoses of Separation: Impact of COVID-19 on Pediatric Emergency Department Visits: A Multicenter Study. J Emerg Med. 2022;63(6):723-8.

Freedman J, Leibovitz E, Sergienko R, Levy A. Risk factors for hospitalization at the pediatric intensive care unit among infants and children younger than 5 years of age diagnosed with infectious diseases. Pediatr Neonatol. 2023;64(2):133-9.

Zhan Z, Lin X, Li G, Zeng J, Su D, Liao J, et al. Renal abscess complicating acute pyelonephritis in children: Two cases report and literature review. Medicine (Baltimore). 2023;102(48):e36355.

Sahu SK, Pradhan DD, Gudu RK, Tripathy SK, Jena P. Prevalence of Acute Bacterial Infections and Their Antibiotic Sensitivity Pattern in Children With Severe Acute Malnutrition From a Tertiary Care Hospital of Odisha. Cureus. 2024;16(7):e65280.

De Silva M, Kolombage P, Kasthuri S. An ovarian torsion in a 2-year-old girl: a case report. J Med Case Rep. 2020;14(1):194.

Pourabhari Langroudi A, Shokri Varniab Z, Nabavizadeh B, Neishabouri A, Kajbafzadeh AM. A novel endoscopic approach for management of hutch diverticulum concomitant vesicoureteral reflux with dextranomer/hyaluronic acid copolymer injection. J Pediatr Urol. 2023;19(3):321.e1-.e7.

Coon ER, Greene T, Fritz J, Desai AD, Ray KN, Hersh AL, et al. A multicenter randomized trial to compare automatic versus as-needed follow-up for children hospitalized with common infections: The FAAN-C trial protocol. J Hosp Med. 2024;19(10):977-87.

Uçan AB, Şencan A. Large congenital bladder diverticula in children. Urologia. 2022;89(3):469-73.

Liao C, He Z, Wang X, Guo P, Xiong W. Laparoscopic surgery for female posterior urethral bladder diverticulum with bladder outlet obstruction: A case report. Medicine (Baltimore). 2023;102(35):e34971.

Sánchez-Rosado M, Reis JD, Jaleel MA, Clipp K, Mangona KLM, Brown LS, et al. Impact of Size for Gestational Age on Multivariate Analysis of Factors Associated with Necrotizing Enterocolitis in Preterm Infants: Retrospective Cohort Study. Am J Perinatol. 2024;41(11):1544-53.

Gkalonaki I, Anastasakis M, Panteli C, Patoulias I. Hutch diverticulum: from embryology to clinical practice. Folia Med Cracov. 2022;62(4):57-62.

Shirane S, Hamada R, Morikawa Y, Harada R, Hamasaki Y, Ishikura K, et al. Frequency and severity of hyponatremia in healthy children with acute illness. Pediatr Nephrol. 2025;40(3):765-72.

Güneş A, Fidan S, Dulkadir R, Ünlü E. Evaluation of risk factors associated with first episode febrile seizure. Eur Rev Med Pharmacol Sci. 2021;25(22):7089-92.

Adeleye QA, Ndubuisi EC, Isa FA. Etiologic and Anti-microbial Susceptibility Profiles of Bacterial Urinary Tract Infection and Bacterial Enteritis among Children at a Private Multi-Specialty Healthcare Facility in Abuja, Nigeria: A 5-Year Separate and Comparative Review. Niger J Clin Pract. 2024;27(1):35-46.

Li Z, Zhang X, Chen H, Zeng H, Wu J, Wang Y, et al. Empagliflozin in children with glycogen storage disease-associated inflammatory bowel disease: a prospective, single-arm, open-label clinical trial. Sci Rep. 2024;14(1):8630.

Diao M, Li L, Ming AX, Yang CZ, Xie XH, Cheng W. Efficacy of Laparoscopic Management of Posterior Urethral Diverticulum in Anorectal Malformations. Eur Urol. 2023;83(1):55-61.

Sah BK, Chaudhary S, Pahari A, Ghimire A, Sah RK, Sah AK, et al. Dysentery and leg ulcer as an atypical presentation of systemic lupus erythematosus: A case report. Medicine (Baltimore). 2022;101(50):e32201.

Kaufman DA, Berenz A, Itell HL, Conaway M, Blackman A, Nataro JP, et al. Dose escalation study of bovine lactoferrin in preterm infants: getting the dose right. Biochem Cell Biol. 2021;99(1):7-13.

McMullan BJ, Valentine JC, Hall L, Thursky K. Disease and economic burden of infections in hospitalised children in New South Wales, Australia. Aust Health Rev. 2022;46(4):471-7.

Reddy R. Concomitant occurrence of pyelocalyceal diverticulum and ipsilateral large sized orthotopic ureterocele in an adult: a rare association. CEN Case Rep. 2022;11(4):458-62.

Ruiz Domínguez JA, Molina Gutiérrez M, de Miguel Cáceres C, Martín Espín I, Plata Gallardo M, Martín Sánchez J. Collateral damage in pediatric scenarios requiring urgent care during the COVID-19 pandemic. Emergencias. 2021;33(3):236-8.

Tufon KA, Fokam DPY, Kouanou YS, Meriki HD. Case report on a swift shift in uropathogens from Shigella flexneri to Escherichia coli: a thin line between bacterial persistence and reinfection. Ann Clin Microbiol Antimicrob. 2020;19(1):31.

Gubatan J, Nielsen OH, Levitte S, Juhl CB, Maxwell C, Streett SE, et al. Biologics During Pregnancy in Women With Inflammatory Bowel Disease and Risk of Infantile Infections: A Systematic Review and Meta-Analysis. Am J Gastroenterol. 2021;116(2):243-53.

Merzon E, Israel A, Ashkenazi S, Rotem A, Schneider T, Faraone SV, et al. Attention-Deficit/Hyperactivity Disorder Is Associated With Increased Rates of Childhood Infectious Diseases: A Population-Based Case-Control Study. J Am Acad Child Adolesc Psychiatry. 2023;62(2):253-60.e1.

Buel KL, Wilcox J, Mingo PT. Acute Abdominal Pain in Children: Evaluation and Management. Am Fam Physician. 2024;110(6):621-31.

Dairiki Shortliffe LM. Urinary tract infections in infants and children. 8 ed. 1. Philadelphia: WB Saunders; 2020. 6(1).:1846–84

Downloads

Published

2025-07-10