PREVALENCE OF OA KNEE PAIN AMONG HOUSEHOLD FEMALES AND ITS IMPACT ON THEIR QUALITY OF LIFE IN SUKKUR

Authors

  • Dr. Muskan Feroz Mangi Royal institute of Physiotherapy and Rehabilitation Sciences, Sukkur affiliated with LUMHS, Jamshoro. Author
  • Dr Karam Wassan Royal institute of Physiotherapy and Rehabilitation Sciences, Sukkur affiliated with LUMHS, Jamshoro. Author
  • Dr Murk Jamali Royal institute of Physiotherapy and Rehabilitation Sciences, Sukkur affiliated with LUMHS, Jamshoro. Author
  • Dr. Kousar Fatima Royal institute of Physiotherapy and Rehabilitation Sciences, Sukkur affiliated with LUMHS, Jamshoro. Author
  • Dr. Tayyaba Salam Royal institute of Physiotherapy and Rehabilitation Sciences, Sukkur affiliated with LUMHS, Jamshoro. Author
  • Professor Dr zohaib Anwer Solangi Royal institute of Physiotherapy and Rehabilitation Sciences, Sukkur affiliated with LUMHS, Jamshoro. Author

DOI:

https://doi.org/10.71000/yr7ray39

Keywords:

osteoarthritis; knee pain; quality of life; women; household work; cross-sectional study; Sukkur; Pakistan

Abstract

Background: Knee osteoarthritis (OA) is a common cause of pain, functional limitation, and reduced quality of life. Women engaged in household work may experience knee symptoms during middle adulthood. This study aimed to determine the proportion of self-reported knee pain among women engaged in household work in Sukkur and examine its association with quality of life.

Methods: This cross-sectional study included 384 women aged 35-57 years in Sukkur. Participants were recruited through non-probability convenience sampling from households and the Physical Therapy Outpatient Department of Hidayat Hospital. Quality of life was assessed using a modified SF-36, and pain intensity was assessed using the Visual Analogue Scale (VAS) within a structured questionnaire. Data were collected through face-to-face interviews. No clinical examination or radiographic assessment was documented to confirm knee osteoarthritis.

Results: The mean age of the participants was 45.4 ± 6.5 years. Of 384 participants, 151 (39.3%) reported study-defined knee pain. Pain-intensity data were available for 150 participants, of whom 100 (66.7%) reported mild pain, 35 (23.3%) moderate pain, and 15 (10.0%) severe pain. Participants reporting knee pain had significantly lower quality-of-life scores than those without reported knee pain (25.21 ± 6.75 vs 30.11 ± 7.73). The mean difference was -4.90 (95% CI, -6.41 to -3.39), t(382) = -6.37, p < 0.001, with a standardized mean difference of 0.67. Quality-of-life scores did not differ significantly across reported pain-intensity categories (F(2,146) = 2.55, p = 0.082).

Conclusions: In this convenience sample, 39.3% of participants reported knee pain, and reported knee pain was associated with lower quality-of-life scores. Because the sample was selected using non-probability convenience sampling and included outpatient participants, this proportion should not be interpreted as a population prevalence estimate for all women in Sukkur. In addition, because no clinical or radiographic diagnostic criteria were documented, the findings refer to self-reported knee pain rather than confirmed knee osteoarthritis.

References

Gelber AC. Knee osteoarthritis. Annals of internal medicine. 2024;177(9):ITC129-ITC44.

Du X, Liu Zy, Tao Xx, Mei Yl, Zhou Dq, Cheng K, et al. Research progress on the pathogenesis of knee osteoarthritis. Orthopaedic surgery. 2023;15(9):2213-24.

Giorgino R, Albano D, Fusco S, Peretti GM, Mangiavini L, Messina C. Knee osteoarthritis: epidemiology, pathogenesis, and mesenchymal stem cells: what else is new? An update. International journal of molecular sciences. 2023;24(7):6405.

Wolf DF, Carvalho C, Padovez RdFCM, de Oliveira MPB, da Silva Serrão PRM. Effects of physical exercise on muscle function of the knee, pain and quality of life in postmenopausal women with knee osteoarthritis: A systematic review with meta-analysis. Musculoskeletal Science and Practice. 2024;71:102929.

Øiestad BE, Juhl CB, Culvenor AG, Berg B, Thorlund JB. Knee extensor muscle weakness is a risk factor for the development of knee osteoarthritis: an updated systematic review and meta-analysis including 46 819 men and women. British journal of sports medicine. 2022;56(6):349-55.

Sulastri D, Arnadi A, Afriwardi A, Desmawati D, Amir A, Irawati N, et al. Risk factor of elevated matrix metalloproteinase-3 gene expression in synovial fluid in knee osteoarthritis women. PLoS One. 2023;18(3):e0283831.

Distefano G, Harrison S, Lynch J, Link TM, Kramer PA, Ramos SV, et al. Skeletal muscle composition, power, and mitochondrial energetics in older men and women with knee osteoarthritis. Arthritis & Rheumatology. 2024;76(12):1764-74.

Qiao L, Li M, Deng F, Wen X, Deng H, Xue Z, et al. Epidemiological trends of osteoarthritis at the global, regional, and national levels from 1990 to 2021 and projections to 2050. Arthritis Research & Therapy. 2025;27(1):199.

Cao F, Xu Z, Li X-X, Fu Z-Y, Han R-Y, Zhang J-L, et al. Trends and cross-country inequalities in the global burden of osteoarthritis, 1990–2019: A population-based study. Ageing Research Reviews. 2024;99:102382.

Malik FB, Memon AG, Shah S, Latif D, Afzal MF, Memon SA. Prevalence Of Knee Osteoarthritis And Quality Of Life Among Middle Aged Adults Of Pakistan: soi: 21-2017/re-trjvol06iss01p280. The Rehabilitation Journal. 2022;6(01):280-3.

Badshah Y, Shabbir M, Hayat H, Fatima Z, Burki A, Khan S, et al. Genetic markers of osteoarthritis: early diagnosis in susceptible Pakistani population. Journal of Orthopaedic surgery and Research. 2021;16(1):124.

Yahaya I, Wright T, Babatunde OO, Corp N, Helliwell T, Dikomitis L, et al. Prevalence of osteoarthritis in lower middle-and low-income countries: a systematic review and meta-analysis. Rheumatology international. 2021;41(7):1221-31.

Li Y, Xie W, Xiao W, Dou D. Progress in osteoarthritis research by the National Natural Science Foundation of China. Bone Research. 2022;10(1):41.

Kandasamy G, Almaghaslah D, Almanasef M, Almeleebia T, Vasudevan R, Siddiqua A, et al. An evaluation of knee osteoarthritis pain in the general community—Asir region, Saudi Arabia. Plos one. 2024;19(1):e0296313.

Dashtian M, Tavafian SS, Shirazi KK, Yazdanpanah P, Maghbouli R, Shojaei S. Knee osteoarthritis in Iranian women: A cross-sectional study from Yassoj, Iran. 2023.

Unverzagt S, Bergmann A, Denny K, Frese T, Hirpa S, Weyer J. Physically demanding occupations among females and sex-related differences to develop osteoarthritis of the hip: a systematic review and meta-analysis. Journal of Occupational Medicine and Toxicology. 2024;19(1):14.

Aw NM-Y, Yeo S-J, Wylde V, Wong SB, Chan D, Thumboo J, et al. Impact of pain sensitisation on the quality of life of patients with knee osteoarthritis. RMD open. 2022;8(1):e001938.

Wojcieszek A, Kurowska A, Majda A, Liszka H, Gądek A. The impact of chronic pain, stiffness and difficulties in performing daily activities on the quality of life of older patients with knee osteoarthritis. International journal of environmental research and public health. 2022;19(24):16815.

Tanvir A, Maryam G. ASSESSMENT OF QUALITY OF LIFE IN KNEE OSTEOATHRITIS PATIENTS. Journal of Medical & Health Sciences Review. 2025;2(3).

Chang J, Yuan Y, Fu M, Wang D. Health-related quality of life among patients with knee osteoarthritis in Guangzhou, China: a multicenter cross-sectional study. Health and quality of life outcomes. 2023;21(1):50.

Puspitaningrum G, Wijianto S. Hubungan Antara Intensitas Nyeri Dengan Kualitas Hidup Pada Pasien Osteoarthritis Knee: Universitas Muhammadiyah Surakarta; 2021.

Feki A, Sellami I, Ellouze F, Yahya M, Baklouti S, Elleuch M. Quality of life assessment in patients with knee osteoarthritis. European Psychiatry. 2024;67(S1):S421-S.

Xue F, Wang W, Shang L, Zhou G, Kang S, Tai D. Temporal trends and future projections of hip/knee osteoarthritis burden attributable to metabolic risk in women of reproductive age (1990–2021): A multidimensional analysis across 204 countries and territories. 2025.

Downloads

Published

2026-07-30

How to Cite

1.
Dr. Muskan Feroz Mangi, Dr Karam Wassan, Dr Murk Jamali, Dr. Kousar Fatima, Dr. Tayyaba Salam, Professor Dr zohaib Anwer Solangi. PREVALENCE OF OA KNEE PAIN AMONG HOUSEHOLD FEMALES AND ITS IMPACT ON THEIR QUALITY OF LIFE IN SUKKUR. IJHR [Internet]. 2026 Jul. 30 [cited 2026 Aug. 19];4(7):1-6. Available from: https://insightsjhr.com/index.php/home/article/view/1738