PREVALENCE OF SURGICAL SITE INFECTIONS FOLLOWING ELECTIVE KIDNEY TRANSPLANTATION

Authors

DOI:

https://doi.org/10.71000/kg3v5s07

Keywords:

Cross-Sectional Studies, Diabetes Mellitus, Immunosuppression, , Kidney Transplantation, Postoperative Complications, Prevalence, Risk Factors, Surgical Site Infection

Abstract

Background: Surgical site infections (SSIs) are a major postoperative complication in kidney transplant recipients, compromising graft outcomes and increasing healthcare burden. Immunosuppression, comorbid conditions, and perioperative factors contribute to the heightened risk of infections in this population.

Objective: To evaluate the prevalence and associated risk factors of SSIs among patients undergoing elective kidney transplantation at a tertiary care center.

Methods: A cross-sectional study was conducted over eight months at a tertiary hospital in Lahore. A total of 200 adult patients undergoing elective kidney transplantation were enrolled using consecutive sampling. SSIs were identified based on CDC criteria within 30 days postoperatively. Data were collected on demographic, clinical, and intraoperative variables. Statistical analysis included univariate and multivariate logistic regression to identify independent risk factors. All procedures were conducted in compliance with ethical guidelines and IRB approval.

Results: The overall prevalence of SSIs was 17%, with superficial infections accounting for 58.8% of cases. Significant risk factors included diabetes mellitus (AOR: 1.96; 95% CI: 1.02–3.76), surgical duration >3 hours (AOR: 2.83; 95% CI: 1.45–5.54), use of surgical drains (AOR: 3.12; 95% CI: 1.61–6.03), and low serum albumin levels (AOR: 2.27; 95% CI: 1.13–4.56). These findings indicate a strong correlation between modifiable clinical factors and SSI development.

Conclusion: SSIs remain a significant concern in kidney transplant patients. Identification and management of modifiable risk factors can substantially reduce infection rates, improve graft outcomes, and support evidence-based infection control practices in transplant surgery.

Author Biographies

  • Mustafeez Ahmed Wassan, Gambat Institute of Medical Sciences (GIMS), Gambat, Pakistan.

    RMO, Gambat Institute of Medical Sciences (GIMS), Gambat, Pakistan.

  • Muhammad Hassam Mehdi, Peshawar General Hospital, Peshawar, Pakistan.

    Medical Officer, Department of Surgery & Allied, Peshawar General Hospital, Peshawar, Pakistan.

  • Talha Adil, Combined Military Hospital, Muzaffarabad, Pakistan.

    House Officer, Combined Military Hospital, Muzaffarabad, Pakistan.

  • Muneeb Islam, Abdul Wali Khan University, Mardan, Pakistan.

    Lecturer, Department of Microbiology, Faculty of Chemical and Life Sciences, Abdul Wali Khan University, Mardan, Pakistan.

  • Ijaz Ahmad, Southeast University, Nanjing, China.

    State Key Laboratory of Bioelectronics, School of Biological Sciences & Biomedical Engineering, Southeast University, Nanjing, China.

  • Ali Sabir Hussain sabir, Liaquat College of Medicine and Dentistry, Karachi, Pakistan.

    Final Year MBBS Student, Liaquat College of Medicine and Dentistry, Karachi, Pakistan.

  • Eman Aslam, Wah Medical College, Islamabad, Pakistan.

    Final Year MBBS Student, Wah Medical College, Islamabad, Pakistan.

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Published

2025-09-16

How to Cite

1.
Wassan MA, Muhammad Hassam Mehdi, Talha Adil, Muneeb Islam, Ijaz Ahmad, Ali Sabir Hussain sabir, et al. PREVALENCE OF SURGICAL SITE INFECTIONS FOLLOWING ELECTIVE KIDNEY TRANSPLANTATION. IJHR [Internet]. 2025 Sep. 16 [cited 2025 Sep. 25];3(5 (Health and Allied):117-24. Available from: https://insightsjhr.com/index.php/home/article/view/1365