EVALUATION AND PREVALENCE OF RENAL SYSTEM PATHOLOGIES ON COMPUTED TOMOGRAPHY KIDNEY, URETER AND BLADDER (CT KUB) AT HAYATABAD MEDICAL COMPLEX PESHAWAR

Authors

  • Muhammad Zeeshan Peshawar Institute of Medical Sciences (PIMS), Peshawar, Pakistan. Author
  • Sehrish Malghalara NCS University System, Peshawar, Pakistan. Author
  • Aleena Khan International College of Health Sciences (ICHS), Peshawar, Pakistan. Author
  • Sapna Mumtaz Alkhidmat Hospital, Peshawar, Pakistan. Author
  • Abdul Salam WMIAHS – Gandhara University, Peshawar, Pakistan. Author
  • Abdul Wadood NCS University System, Peshawar, Pakistan. Author

DOI:

https://doi.org/10.71000/ewnfcb10

Keywords:

Renal Pathology, Urolithiasis, Hydronephrosis, , Hydroureter, , Prevalence, Computed Tomography, Kidney Calculi

Abstract

Background: Hydronephrosis, hydroureter, and urolithiasis are among the most frequently encountered renal pathologies presenting with overlapping symptoms but requiring distinct management approaches. Conventional imaging methods such as ultrasonography and intravenous pyelography, although useful, often fail to precisely distinguish between obstructive and non-obstructive causes of hydronephrosis. Computed Tomography of the Kidneys, Ureters, and Bladder (CT KUB) offers superior sensitivity, specificity, and anatomical detail, making it the preferred diagnostic tool for evaluating urinary tract calculi and obstruction with enhanced clinical accuracy.

Objective: To assess renal system pathologies using CT KUB and determine its diagnostic value in differentiating obstructive from non-obstructive hydronephrosis and related urinary tract abnormalities.

Methods: A retrospective study was conducted at the Radiology Department of Hayatabad Medical Complex, Peshawar, analyzing CT KUB reports obtained between July 2022 and July 2023. Data were retrieved from 5,180 patient records and included demographic characteristics (age, gender) and radiological findings related to hydronephrosis, hydroureter, and urinary calculi. Imaging was performed using a 128-slice GE CT scanner, and findings were reviewed through the Picture Archiving and Communication System (PACS). Statistical analysis was performed using SPSS version 26.0, applying descriptive and inferential statistics with significance set at p < 0.05.

Results: Out of 5,180 patients, 8.63% of males and 6.24% of females had obstructive hydronephrosis, while 25.08% of males and 16.37% of females exhibited non-obstructive hydronephrosis. Hydroureter was observed in 27.03% of males and 18.68% of females, confirming a clear male predominance. Renal calculi were identified in 60.64% of all cases, most commonly located within the kidneys, followed by the pelvic ureteric junction and proximal ureter. CT KUB effectively detected and classified urinary tract stones and obstructions with high precision.

Conclusion: CT KUB proved to be a highly reliable and accurate imaging modality for evaluating renal system pathologies. It effectively differentiated obstructive from non-obstructive hydronephrosis and precisely identified the presence and location of urolithiasis. The observed male predominance underscores the need for preventive strategies and timely imaging evaluation to reduce disease burden and complications.

Author Biographies

  • Muhammad Zeeshan, Peshawar Institute of Medical Sciences (PIMS), Peshawar, Pakistan.

    Radiology Technologist, Peshawar Institute of Medical Sciences (PIMS), Peshawar, Pakistan.

  • Sehrish Malghalara, NCS University System, Peshawar, Pakistan.

    Department of Radiology Technology, NCS University System, Peshawar, Pakistan.

  • Aleena Khan, International College of Health Sciences (ICHS), Peshawar, Pakistan.

    Demonstrator Radiology Technology, International College of Health Sciences (ICHS), Peshawar, Pakistan.

  • Sapna Mumtaz, Alkhidmat Hospital, Peshawar, Pakistan.

    Radiology Technologist, Alkhidmat Hospital, Peshawar, Pakistan.

  • Abdul Salam, WMIAHS – Gandhara University, Peshawar, Pakistan.

    Lecturer Medical Imaging Technology, WMIAHS – Gandhara University, Peshawar, Pakistan.

  • Abdul Wadood, NCS University System, Peshawar, Pakistan.

    Assistant Professor Radiology, NCS University System, Peshawar, Pakistan.

References

Ouyang C, Yang X, Xie J, Hu J. Analysis of the Application Value of X-Ray Digital Tomographic Fusion Technique in Urinary System Diseases. J Healthc Eng. 2022;2022:6294752.

Liu D, Liu J, Li Z, Ge C, Guo H, Song S, et al. The association between renal pelvis urine density and the risk of severe infectious complications in patient with symptom-free hydronephrosis after shock wave lithotripsy: a multi-center prospective study. Urolithiasis. 2024;52(1):72.

Merindol I, Vachon C, Juette T, Dunn M. Benign ureteral obstruction in cats: Outcome with medical management. J Vet Intern Med. 2023;37(3):1047-58.

Innes GD, Wishart I, Lau T, Islam A, Gourlay K, Scheuermeyer FX. Can plain film radiography improve the emergency department detection of clinically important urinary stones? Am J Emerg Med. 2021;50:449-54.

Wang M, Zhang Y, Tong H, Liu B, Chen J, Ma Q, et al. Comparison of ureteral stone measurements for predicting the efficacy of a single session of extracorporeal shockwave lithotripsy: one-, two-, and three-dimensional computed tomography measurements. Urolithiasis. 2024;52(1):43.

Yang B, Zhu Y, Zhou Q, Shu C. Correlation of the Degree of Hydronephrosis and Computed Tomography Value of Calculi with Efficacy of Ureteroscopic Lithotripsy in Patients with Upper Urinary Tract Infectious Calculi. Arch Esp Urol. 2023;76(6):377-82.

Durant EJ, Engelhart DC, Ma AA, Warton EM, Arasu VA, Bernal R, et al. CT Use Reduction In Ostensive Ureteral Stone (CURIOUS). Am J Emerg Med. 2023;67:168-75.

Khan RU, Nazim SM, Anwar S. CT-Based Predictors of Spontaneous Ureteral Stone Passage. J Coll Physicians Surg Pak. 2024;34(8):879-84.

Guler Y, Erbin A, Kafkasli A, Ozmerdiven G. Factors affecting success in the treatment of proximal ureteral stones larger than 1 cm with extracorporeal shockwave lithotripsy in adult patients. Urolithiasis. 2021;49(1):51-6.

Cooper JL, François N, Sourial MW, Miyagi H, Rose JR, Shields J, et al. The Impact of Ureteral Access Sheath Use on the Development of Abnormal Postoperative Upper Tract Imaging after Ureteroscopy. J Urol. 2020;204(5):976-81.

Kitano H, Shigemoto N, Koba Y, Hara T, Seiya K, Omori K, et al. Indwelling catheterization, renal stones, and hydronephrosis are risk factors for symptomatic Staphylococcus aureus-related urinary tract infection. World J Urol. 2021;39(2):511-6.

Huang B, Lu G, Zhao Y, Tu W, Shao Y, Wang D, et al. The mean Hounsfield unit range acquired from different slices produces superior predictive accuracy for pyonephrosis in obstructive uropathy. Investig Clin Urol. 2024;65(3):286-92.

Dong X, Wang D, Zhang H, You S, Pan W, Pang P, et al. No staghorn calculi and none/mild hydronephrosis may be risk factors for severe bleeding complications after percutaneous nephrolithotomy. BMC Urol. 2021;21(1):107.

Güler Y. Non-contrast computed tomography-based factors in predicting ESWL success: A systematic review and meta-analysis. Prog Urol. 2023;33(1):27-47.

Jackman SV, Maganty A, Wolfson AB, Burrows PK, MacPherson C, Vargas NM, et al. Resolution of Hydronephrosis and Pain to Predict Stone Passage for Patients With Acute Renal Colic. Urology. 2022;159:48-52.

Yu J, Li B, Ren BX, Zhang NY, Jin BX, Zhang JJ. Subcapsular renal haematoma after ureteroscopic lithotripsy: a single-centre, retrospective study in China. BMJ Open. 2022;12(11):e062866.

Abbas SK, Al-Omary TSS, Fawzi HA. Ultrasound accuracy in evaluating renal calculi in Maysan province. J Med Life. 2024;17(2):226-32.

Sahin C, Karaca Y, Sobay R, Arikan O, Uslu M, Bicaklioglu F, et al. Ureteral stricture formation after endoscopic removal of obstructing stones: could it be predicted with well-assessed radiological parameters? Urolithiasis. 2024;52(1):34.

Zuo YT, Liu TZ, Li B, Li S, Wang YZ, Chen P, et al. Zero-Intrarenal Pressure Percutaneous Nephrolithotomy for One-Stage Treatment of Non-Acute Infectious Calculous Pyonephrosis: A Strategy to Avert Sepsis. J Endourol. 2024;38(11):1128-33.

Javed N, John A, Khalid Q, Hamza MA. Detection of Urolithiasis Using Non-Contrast Computed Tomography: Urolithiasis Using Non- Contrast Computed Tomography. Pakistan BioMedical Journal. 2022:17- 21

Fallatah M, Jaafari R, Alshammari A, Bashaikh A, Alshehri I, AlSubaie H, et al. Imaging of Kidney Stones: CT Urography, Ultrasound, and Stone Composition Analysis. 2023

Wekhe C, Akagbue VN, Amadi M-JO. Demographic, Clinical and Radiological Findings among Patients with CTU Detected Urolithiasis in a Tertiary Hospital. Journal of Complementary and Alternative Medical Research. 2023;22(1):17-27

Akram H, John A, Ali A, Jamil M, Rasheed L. Role of CT-KUB for Detection of Obstructive and Non-Obstructive Hydronephrosis on The Basis of Frequency of Calculi: CT-KUB for Detection of Obstructive and Non-Obstructive Hydronephrosis on The Basis of Frequency of Calculi. Pakistan BioMedical Journal. 2022:32-5

Khalid B, Maryam S, Zakir M, Farooq SY. Role of Computed Tomography in Patients with Obstructive & Non-Obstructive Kidneys. Ophthalmology Update. 2021;19(3):224-8

Downloads

Published

2025-06-30