COMPARISON OF EYE AXIAL LENGTH AMONG YOUNG AND OLD HEALTHY VOLUNTEERS MEASURED ON TRANSORBITAL ULTRASOUND

Authors

  • Maria Yaseen Khwaja Fareed University of Engineering and Information Technology, Rahim Yar Khan , Pakistan. Author https://orcid.org/0009-0005-6081-6938
  • Shaista Bibi Khwaja Fareed University of Engineering and Information Technology, Pakistan. Author
  • Aiman Naeem Khwaja Fareed University of Engineering and Information Technology, Pakistan. Author
  • Khadija Irshad Khwaja Fareed University of Engineering and Information Technology, Pakistan. Author
  • Ayesha Shahid Khwaja Fareed University of Engineering and Information Technology, Pakistan. Author
  • Aks-E-Qamar Khwaja Fareed University of Engineering and Information Technology, Pakistan. Author
  • Muqadas Tufail Khwaja Fareed University of Engineering and Information Technology, Pakistan. Author
  • Saba Ajmal Khwaja Fareed University of Engineering and Information Technology, Rahim Yar Khan , Pakistan. Author https://orcid.org/0009-0000-1473-728X
  • Ahmad Bilal Khwaja Fareed University of Engineering and Information Technology, Rahim Yar Khan , Pakistan. Author

DOI:

https://doi.org/10.71000/kfn92n42

Keywords:

Eye Axial Length, Transorbital Sonography , Adult, Healthy Volunteers, Intraocular Biometry, Ultrasonography, , Visual Acuity Measurements

Abstract

Background: Transorbital ultrasonography is a non-invasive, accessible, and effective imaging modality for ocular biometry, particularly valuable for measuring axial length—the distance from the anterior corneal surface to the inner retinal layer. Accurate axial length measurement is crucial for calculating intraocular lens (IOL) power, especially in cataract surgery. Establishing normative values across age groups is essential for both diagnostic accuracy and surgical outcomes in ophthalmic care.

Objective: To compare the axial length of the eye between young and older healthy adult volunteers using transorbital ultrasonography.

Methods: This comparative cross-sectional study was conducted from January to April 2025 at Fatima Medical Lab, Rahim Yar Khan. A total of 50 healthy participants (100 eyes), including 27 males (54%) and 23 females (46%), were recruited and divided into two age groups: Group 1 (20–40 years) and Group 2 (41–60 years), with 25 participants in each group. Eye axial length was measured using a 9–12 MHz linear transducer on a GE S6 ultrasound system. Each eye was scanned three times, and the average value was recorded. Data were analyzed using SPSS version 2025. Independent sample t-tests were applied, and p-values <0.05 were considered statistically significant.

Results: The participants had a mean age of 38.92 ± 11.22 years. The overall mean right eye axial length was 23.05 ± 1.4 mm, and the left eye axial length was 23.06 ± 1.6 mm. In Group 1, the right eye axial length averaged 23.40 ± 1.2 mm compared to 22.80 ± 1.3 mm in Group 2 (p = 0.121). The left eye measurements were 24.09 ± 1.0 mm and 23.90 ± 1.2 mm for Groups 1 and 2, respectively (p = 0.558), indicating no statistically significant difference.

Conclusion: This study demonstrates that axial length, as measured by transorbital ultrasonography, shows no significant variation between young and older healthy adults, suggesting it remains relatively stable across adulthood in the absence of ocular or systemic pathology.

Author Biographies

  • Maria Yaseen, Khwaja Fareed University of Engineering and Information Technology, Rahim Yar Khan , Pakistan.

    Lecturer, Institute of Health Sciences, Khwaja Fareed University of Engineering and Information Technology, Rahim Yar Khan , Pakistan.

  • Shaista Bibi, Khwaja Fareed University of Engineering and Information Technology, Pakistan.

    Bachelor of Science in Radiography and Imaging Technology, Institute of Health Sciences, Khwaja Fareed University of Engineering and Information Technology, Pakistan.

  • Aiman Naeem, Khwaja Fareed University of Engineering and Information Technology, Pakistan.

    Bachelor of Science in Radiography and Imaging Technology, Institute of Health Sciences, Khwaja Fareed University of Engineering and Information Technology, Pakistan.

  • Khadija Irshad, Khwaja Fareed University of Engineering and Information Technology, Pakistan.

    Bachelor of Science in Radiography and Imaging Technology, Institute of Health Sciences, Khwaja Fareed University of Engineering and Information Technology, Pakistan.

  • Ayesha Shahid, Khwaja Fareed University of Engineering and Information Technology, Pakistan.

    Bachelor of Science in Radiography and Imaging Technology, Institute of Health Sciences, Khwaja Fareed University of Engineering and Information Technology, Pakistan.

  • Aks-E-Qamar, Khwaja Fareed University of Engineering and Information Technology, Pakistan.

    Bachelor of Science in Radiography and Imaging Technology, Institute of Health Sciences, Khwaja Fareed University of Engineering and Information Technology, Pakistan.

  • Muqadas Tufail, Khwaja Fareed University of Engineering and Information Technology, Pakistan.

    Bachelor of Science in Radiography and Imaging Technology, Institute of Health Sciences, Khwaja Fareed University of Engineering and Information Technology, Pakistan.

  • Saba Ajmal, Khwaja Fareed University of Engineering and Information Technology, Rahim Yar Khan , Pakistan.

    Lecturer, Institute of Health Sciences, Khwaja Fareed University of Engineering and Information Technology, Rahim Yar Khan , Pakistan.

  • Ahmad Bilal, Khwaja Fareed University of Engineering and Information Technology, Rahim Yar Khan , Pakistan.

    Lecturer, Institute of Health Sciences, Khwaja Fareed University of Engineering and Information Technology, Rahim Yar Khan , Pakistan.

References

Nguyen JH, Nguyen-Cuu J, Mamou J, Routledge B, Yee KMP, Sebag J. Vitreous Structure and Visual Function in Myopic Vitreopathy Causing Vision-Degrading Myodesopsia. Am J Ophthalmol. 2021;224:246-53.

Berrones D, Rivera-Cortes M, Monroy-Esquivel L, Becerra-Revollo C, Mayorquin-Ruiz M, Velez-Montoya R. Ultrasound-Guided Pars Plana Vitrectomy. Retina. 2023;43(12):2153-6.

Chee SP, Weikert MP, Wallace R, De Francesco T, Ahmed I, Fram N, et al. Traumatic cataract with iridodialysis. J Cataract Refract Surg. 2024;50(11):1191-6.

Zhu Z, Zou H, Li H, Wu X, Wang Y, Li Z, et al. Repeatability and reproducibility of anterior lens zonule length measurement using ArcScan insight 100 very high-frequency ultrasound. Expert Rev Med Devices. 2023;20(8):703-10.

Sayin N, Kocak I, Pehlivanoğlu S, Pekel G, Er A, Bayramoğlu SE, et al. A quantitative sonoelastography evaluation of ocular and periocular elasticity after intravitreal ranibizumab injection. J Fr Ophtalmol. 2023;46(9):1030-8.

Kaya P, Özdemir Yalçınsoy K, Özdamar Erol Y. The Presence of Optic Disc Drusen in Eyes with Uveitis. Ocul Immunol Inflamm. 2023;31(8):1700-6.

D CP, Dogra A. Posterior microphthalmos with pigmentary retinopathy. BMJ Case Rep. 2020;13(11).

Sariyeva Ismayılov A, Aydin Guclu O, Erol HA. Ocular manifestations in hemodialysis patients and short-term changes in ophthalmologic findings. Ther Apher Dial. 2021;25(2):204-10.

Xu BY, Friedman DS, Foster PJ, Jiang Y, Porporato N, Pardeshi AA, et al. Ocular Biometric Risk Factors for Progression of Primary Angle Closure Disease: The Zhongshan Angle Closure Prevention Trial. Ophthalmology. 2022;129(3):267-75.

Hoerig C, Nguyen JH, Mamou J, Venuat C, Sebag J, Ketterling JA. Machine Independence of Ultrasound-Based Quantification of Vitreous Echodensities. Transl Vis Sci Technol. 2023;12(9):21.

Paniagua-Diaz AM, Nguyen JH, Artal P, Gui W, Sebag J. Light Scattering by Vitreous of Humans With Vision Degrading Myodesopsia From Floaters. Invest Ophthalmol Vis Sci. 2024;65(5):20.

Yeşiltaş YS, Zhou M, Zabor EC, Oakey Z, Singh N, Sedaghat A, et al. Iris freckle: a distinct entity. Br J Ophthalmol. 2024;108(12):1749-54.

Hoerig C, Hoang QV, Mamou J. In-vivo high-frequency quantitative ultrasound-derived parameters of the anterior sclera correlated with level of myopia and presence of staphyloma. Clin Exp Ophthalmol. 2024;52(8):840-52.

Sorkin N, Ohri A, Jung H, Haines L, Sorbara L, Mimouni M, et al. Factors affecting central corneal thickness measurement agreement between Scheimpflug imaging and ultrasound pachymetry in keratoconus. Br J Ophthalmol. 2021;105(10):1371-5.

Huang Y, Cai Y, Peng MQ, Yi TT. Evaluation of the effect of fluid management on intracranial pressure in patients undergoing laparoscopic gynaecological surgery based on the ratio of the optic nerve sheath diameter to the eyeball transverse diameter as measured by ultrasound: a randomised controlled trial. BMC Anesthesiol. 2024;24(1):319.

Drechsler J, Lee A, Maripudi S, Kueny L, Levin MR, Saeedi OJ, et al. Corneal Structural Changes in Congenital Glaucoma. Eye Contact Lens. 2022;48(1):27-32.

Tey KY, Wong QY, Dan YS, Tsai ASH, Ting DSW, Ang M, et al. Association of Aberrant Posterior Vitreous Detachment and Pathologic Tractional Forces With Myopic Macular Degeneration. Invest Ophthalmol Vis Sci. 2021;62(7):7.

Zhong M, Liu S, Luo J, Zhang Q, Yang Z, Zhang S. Application of lacrimal gland ultrasonography in the evaluation of chronic ocular graft-versus-host-disease. Front Immunol. 2025;16:1490390.

Goel R, Shah S, Gupta S, Khullar T, Singh S, Chhabra M, et al. Alterations in retrobulbar haemodynamics in thyroid eye disease. Eye (Lond). 2023;37(17):3682-90.

Wiseman SJ, Tatham AJ, Meijboom R, Terrera GM, Hamid C, Doubal FN, Wardlaw JM, Ritchie C, Dhillon B, MacGillivray T. Measuring axial length of the eye from magnetic resonance brain imaging. BMC ophthalmology. 2022 Feb 5;22(1):54.

Downloads

Published

2025-06-20