ATYPICAL SITES OF OCCURRENCE OF ORAL SQUAMOUS CELL CARCINOMA IN ORAL CAVITY: A CASE SERIES

Abstract

Background: Oral squamous cell carcinoma (OSCC) often presents in recognized sites such as the tongue and buccal mucosa; however, its manifestation in less common anatomical areas can complicate diagnosis and treatment. This case series explores OSCC in atypical locations to illustrate diagnostic challenges and emphasize the importance of broad clinical vigilance.

Case Details: Three cases are reported highlighting unusual presentations of OSCC. The first involves a 78-year-old male with a non-healing ulcer of the right mandibular alveolus diagnosed as moderately differentiated OSCC. The second case details a 51-year-old female presenting with growths on her alveolus and palate, identified as well differentiated OSCC. The third case describes a 52-year-old patient with a non-healing ulcer in the retro-molar trigone, diagnosed as moderately differentiated OSCC. These cases underscore the variable presentations of OSCC and the need for comprehensive evaluation in atypical sites.

Conclusion: The identification of OSCC in non-traditional locations underscores the need for clinicians to maintain an expansive differential diagnosis when evaluating oral lesions. Awareness and education on the variability of OSCC presentations are crucial for timely and accurate diagnosis, which can significantly influence treatment outcomes.