DIVERSE RADIOLOGICAL PATTERNS IN ADULT TUBERCULOSIS
DOI:
https://doi.org/10.71000/3ht4t495Keywords:
Adult Chest X-Ray, Pulmonary Tuberculosis, Radiography, Risk Factors, Smoking, TuberculosisAbstract
Background: Tuberculosis remains a major global health concern, particularly in adult populations where pulmonary involvement shows a wide range of radiographic appearances. Chest X-ray continues to be a fundamental diagnostic tool for early detection and assessment of disease severity, especially in resource-limited settings. However, variability in radiographic patterns, influenced by host factors and underlying conditions such as smoking and metabolic disorders, often complicates accurate diagnosis. Understanding both typical and atypical imaging manifestations is therefore essential for timely diagnosis, appropriate management, and effective disease control.
Objective: To identify and describe the diverse radiological patterns of adult pulmonary tuberculosis and to evaluate their association with underlying conditions, particularly tobacco smoking, in a defined population.
Methods: A prospective observational study was conducted on adult patients undergoing tuberculosis screening at a tertiary care hospital. Chest radiographs were obtained using a Toshiba 500 mA X-ray system with standardized posteroanterior positioning. A convenience sampling technique was employed. Demographic data, clinical history, and radiographic findings were recorded using a structured proforma. Data analysis was performed using SPSS version 20, applying descriptive statistics to summarize clinical characteristics and imaging patterns.
Results: All enrolled patients demonstrated chest X-ray findings consistent with pulmonary tuberculosis. The cohort showed a male predominance, with females also substantially represented. A notable proportion reported a positive family history of tuberculosis. Lifestyle-related risk factors were common, including tobacco smoking and substance abuse, while a smaller subset had pre-existing diabetes mellitus. Radiographically, lung infiltrations were the most frequent finding, followed by consolidations, pleural effusions, and cavitary lesions, while small nodules were relatively uncommon. These findings reflected a broad spectrum of disease severity and radiographic presentation.
Conclusion: Adult pulmonary tuberculosis exhibited considerable radiographic variability influenced by demographic and clinical risk factors. Chest X-ray proved to be a sensitive and practical tool for detecting both early and advanced disease. Integrating radiographic assessment with evaluation of underlying risk factors can enhance diagnostic accuracy and support targeted, context-specific tuberculosis control strategies.
References
World Health Organization. Progress towards achieving global tuberculosis targets and implementation of the UN political declaration on tuberculosis: overview. 2021.
Lawal IO, Abubakar S, Ankrah AO, Sathekge MM. Molecular imaging of tuberculosis. In Elsevier; 2023. p. 37–56.
Macías Gordaliza P. Computer-Aided Assessment of Tuberculosis with Radiological Imaging: From rule-based methods to Deep Learning. 2022.
Stevic R, Odalovic S. Radiological Imaging in Tuberculosis. PETCT Tuberc. 2020;31–42.
Sonuga-Barke EJ, Becker SP, Bölte S, Castellanos FX, Franke B, Newcorn JH, et al. Annual Research Review: Perspectives on progress in ADHD science–from characterization to cause. J Child Psychol Psychiatry. 2023;64(4):506–32.
Zaidi I, Vardha J, Anjum S, Chaudhary S, Bakshi A, Gill JK, et al. Tuberculosis and Pulmonary Co-Infections: Clinical Profiles and Management Strategies. Med Res Arch. 2023;11(12).
Bustin SA,Jellinger KA. Advances in molecular medicine: Unravelling disease complexity and pioneering precision healthcare. Int J Mol Sci. 2023;24(18):14168.17.
Song QS, Zheng CJ, Wang KP, Huang XL, Tartakovsky M, Wáng YXJ. Differences in pulmonary nodular consolidation and pulmonary cavity among drug-sensitive, rifampicin resistant and multi-drug resistant tuberculosis patients: a computerized tomography study with history length matched cases. J Thorac Dis. 2022;14(7):2522.
Chen RY, Yu X, Smith B, Liu X, Gao J, Diacon AH, et al. Radiological and functional evidence of the bronchial spread of tuberculosis: an observational analysis. Lancet Microbe. 2021;2(10):e518 26.
Najjar R. Redefining radiology: a review of artificial intelligence integration in medical imaging. Diagnostics. 2023;13(17):2760
Prakash LK, Mane M, Sahu S, Vimala LR, Jha P, Rebecca G, Manoharan A, Irodi A. Pulmonary Tuberculosis in Immunocompromised Patients: A Review. Indographics. 2024 Dec;3(02):054-71.
Cheng N, Wu S, Luo X, Xu C, Lou Q, Zhu J, You L, Li B. A comparative study of chest computed tomography findings: 1030 cases of drug-sensitive tuberculosis versus 516 cases of drug-resistant tuberculosis. Infection and Drug Resistance. 2021 Mar 18:1115-28.
van Staalduinen EK, Zeineh MM. Medial temporal lobe anatomy. Neuroimaging Clinics of North America. 2022 Aug 1;32(3):475-89.
Jain A, Malhotra A, Arora D, Maqusood M, Kumar S. Assessment of disease activity and complications in patients of pulmonary tuberculosis by high resolution computed tomography. Sudan Journal of Medical Sciences. 2021 Jul 1;16(2):159-77.
Reid WD, Chung F, Hill K. CHEST X-RAYS. Cardiopulmonary Physical Therapy: Management and Case Studies. 2024 Jun 1:141.
Li P, Zhang J, Yuan W, Yu S, Li P, Zhang J, Yuan W, Li P, Zhang J, Yuan W, Li P. Idiopathic interstitial pneumonia. InRadiology of Infectious and Inflammatory Diseases-Volume 3: Heart and Chest 2023 Nov 3 (pp. 309-323). Singapore: Springer Nature Singapore.
Innes AL, Martinez A, Hoang GL, Nguyen TBP, Vu VH, Luu THT, et al. Active case finding to detect symptomatic and subclinical pulmonary tuberculosis disease: implementation of computer-aided detection for chest radiography in Viet Nam. Western Pac Surveill Response J. 2024;15(4):1-12.
Teixeira Marques F, Estêvão R, Mota CP, Lousan N. Laryngeal tuberculosis, the great deceiver: A series of 10 cases. Indian J Tuberc. 2024;71(3):238-41.
Zawedde J, Abelman R, Musisi E, Nyabigambo A, Sanyu I, Kaswabuli S, et al. Lung function and health-related quality of life among adult patients following pulmonary TB treatment. Int J Tuberc Lung Dis. 2024;28(9):419-26.
Mokti K, Md Isa Z, Sharip J, Abu Bakar SN, Atil A, Hayati F, et al. Predictors of delayed sputum smear conversion among pulmonary tuberculosis patients in Kota Kinabalu, Malaysia: A retrospective cohort study. Medicine (Baltimore). 2021;100(31):e26841.
Park HY, Kang D, Shin SH, Choi H, Jang SH, Lee CH, et al. Pulmonary Tuberculosis and the Incidence of Lung Cancer among Patients with Chronic Obstructive Pulmonary Disease. Ann Am Thorac Soc. 2022;19(4):640-8.
Giridharan P, Selvaraju S, Rao R, Rade K, Thiruvengadam K, Asthana S, et al. Recurrence of pulmonary tuberculosis in India: Findings from the 2019-2021 nationwide community-based TB prevalence survey. PLoS One. 2023;18(12):e0294254.
Meena R, Goyal A, Keshri SK, Khurana AK. Unusual presentation of chronic eosinophilic pneumonia with mild peripheral eosinophilia. BMJ Case Rep. 2021;14(2).
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