COMPARATIVE EFFECTS OF ACTIVITY-BASED MIRROR TRAINING WITH OR WITHOUT RHYTHMIC AUDITORY STIMULATION TO IMPROVE LOWER EXTREMITY FUNCTIONS IN SUBACUTE STROKE PATIENTS: A RANDOMIZED CONTROLLED TRIAL

Authors

  • Nazish Mushtaq Skin360 Clinic, Lahore,  Punjab, Pakistan Author
  • Hifsa Waheed Riphah International University, Lahore, Punjab, Pakistan Author
  • Fatima Tariq Riphah International University, Lahore, Punjab, Pakistan Author
  • Laiba Khalid Butt University of Balochistan, Quetta, Balochistan, Pakistan,  Author
  • Fizza Sabir CMH Lahore Medical College (Affiliated with UHS), Lahore, Punjab, Pakistan. Author
  • Alishah Malik Sehat Medical Complex (University of Lahore), Punjab, Pakistan. Author
  • Azka Yaseen Gulzar Family Hospital Sialkot, Punjab Pakistan Author

DOI:

https://doi.org/10.71000/jceb8r64

Keywords:

Activities of Daily Living, Auditory Perception, Gait, Mirror Neurons, Rehabilitation, Stroke, Walking Speed

Abstract

Background: Stroke is a leading cause of long-term disability worldwide, with lower limb impairments often resulting in reduced mobility, impaired balance, and loss of independence. Rehabilitation strategies targeting the restoration of motor function and gait are therefore essential to improve quality of life and reintegration into daily activities. Mirror therapy has been recognized as an effective approach to enhance motor recovery, while rhythmic auditory stimulation provides external cues that may further facilitate gait symmetry and walking performance.

Objective: The purpose of this study was to compare the effects of activity-based mirror training (ABMT) with and without rhythmic auditory stimulation (RAS) on lower extremity function in subacute stroke patients.

Methods: This randomized controlled trial was conducted at THQ Hospital Muridke, Sheikhupura, and Muhammad Ali Physiotherapy Clinic and Rehabilitation Centre, Lahore, between June and December 2023. A total of 40 participants were recruited using non-probability convenience sampling, of which 36 completed the study. Participants aged 45–65 years with unilateral hemiplegia in the subacute phase were randomized into two groups using a flip coin method. Group A received ABMT with RAS, while Group B received ABMT without RAS. Interventions were delivered in 30 sessions over six weeks. Outcomes were assessed at baseline and post-intervention using the Fugl-Meyer Assessment for the Lower Extremity (FMA-LE), the Rivermead Visual Gait Assessment (RVGA), and the 10-Meter Walk Test (10-MWT). Data were analyzed using SPSS version 26.

Results: The mean age of participants was 55.66 ± 6.92 years. In the FMA-LE, scores improved from 14.16 ± 1.94 to 23.38 ± 1.78 in the ABMT with RAS group compared to 15.16 ± 2.00 to 22.00 ± 1.13 in the ABMT group (p = 0.015). The 10-MWT improved from 0.704 ± 0.224 m/s to 1.21 ± 0.178 m/s in the ABMT with RAS group versus 0.653 ± 0.230 m/s to 1.032 ± 0.144 m/s in the ABMT group (p = 0.001). RVGA scores decreased from 19.94 ± 4.56 to 12.61 ± 1.61 in the ABMT with RAS group, while the ABMT group improved from 21.77 ± 5.73 to 16.55 ± 4.39 (p = 0.003).

Conclusion: Both interventions significantly improved motor recovery and gait function in subacute stroke patients. However, ABMT combined with RAS produced superior improvements in lower limb motor control, gait velocity, and gait quality, supporting its role as an effective adjunct to stroke rehabilitation programs. 

Author Biographies

  • Nazish Mushtaq, Skin360 Clinic, Lahore,  Punjab, Pakistan

     Physiotherapist, Skin360 Clinic, Lahore,  Punjab, Pakistan

  • Hifsa Waheed, Riphah International University, Lahore, Punjab, Pakistan

    Physiotherapist, Faculty of Rehabilitation & Allied Health Sciences, Riphah International University, Lahore, Punjab, Pakistan

  • Fatima Tariq, Riphah International University, Lahore, Punjab, Pakistan

    Senior Lecturer, Faculty of Rehabilitation & Allied Health Sciences, Riphah International University, Lahore, Punjab, Pakistan

  • Laiba Khalid Butt, University of Balochistan, Quetta, Balochistan, Pakistan, 

     Physiotherapist, Department of Physiotherapy, University of Balochistan, Quetta, Balochistan, Pakistan, 

  • Fizza Sabir, CMH Lahore Medical College (Affiliated with UHS), Lahore, Punjab, Pakistan.

    Doctor of Physical Therapy (DPT), CMH Lahore Medical College (Affiliated with UHS), Lahore, Punjab, Pakistan.

  • Alishah Malik, Sehat Medical Complex (University of Lahore), Punjab, Pakistan.

    Physiotherapist, Sehat Medical Complex (University of Lahore), Punjab, Pakistan.

  • Azka Yaseen, Gulzar Family Hospital Sialkot, Punjab Pakistan

    Physiotherapist, Gulzar Family Hospital Sialkot, Punjab Pakistan

References

Feigin VL, Brainin M, Norrving B, Martins S, Sacco RL, Hacke W, et al. World Stroke Organization (WSO): Global Stroke Fact Sheet 2022. International journal of stroke: official journal of the International Stroke Society. 2022;17(1):18-29.

Shaikh BA, Gurbakhshani KM, Muhammad SK. Frequency of atrial fibrillation in patients of ischemic stroke. SZMC. 2017;31:120-6.

Gunduz ME, Bucak B, Keser Z. Advances in Stroke Neurorehabilitation. 2023;12(21):6734.

Kundi MK, Spence NJ. Efficacy of mirror therapy on lower limb motor recovery, balance and gait in subacute and chronic stroke: A systematic review. 2023;28(2): e1997.

Martínez CAL, Pérez LdCA, Gutiérrez AGT, Casas ICMJM. Music therapy as a therapeutic modality regulating emotions in early retired people. 2021;25(1):92-106.

Wang L, Peng J-l, Xiang W, Huang Y-j, Chen A-l. Effects of rhythmic auditory stimulation on motor function and balance ability in stroke: A systematic review and meta-analysis of clinical randomized controlled studies. 2022;16.

Cheng DK, Nelson M, Brooks D, Salbach NM. Validation of stroke-specific protocols for the 10-meter walk test and 6-minute walk test conducted using 15-meter and 30-meter walkways. Topics in stroke rehabilitation. 2020;27(4):251-61.

Hlomayi BY. Effectivity of Combined Rhythmic Auditory Stimulation Rehabilitation Approach on Gait post Stroke. 2023.

Cho H, Kim KJJoS, Diseases C. Effects of action observation training with auditory stimulation on static and dynamic balance in chronic stroke patients. 2020;29(5):104775.

Zhang B, Li D, Liu Y, Wang J, Xiao Q. Virtual reality for limb motor function, balance, gait, cognition and daily function of stroke patients: A systematic review and meta-analysis. J Adv Nurs. 2021;77(8):3255-73.

Meng L, Liang Q, Yuan J, Li S, Ge Y, Yang J, et al. Vestibular rehabilitation therapy on balance and gait in patients after stroke: a systematic review and meta-analysis. BMC Med. 2023;21(1):322.

Veldema J, Gharabaghi A. Non-invasive brain stimulation for improving gait, balance, and lower limbs motor function in stroke. J Neuroeng Rehabil. 2022;19(1):84.

Reddy RS, Gular K, Dixit S, Kandakurti PK, Tedla JS, Gautam AP, et al. Impact of Constraint-Induced Movement Therapy (CIMT) on Functional Ambulation in Stroke Patients-A Systematic Review and Meta-Analysis. Int J Environ Res Public Health. 2022;19(19).

Demeco A, Zola L, Frizziero A, Martini C, Palumbo A, Foresti R, et al. Immersive Virtual Reality in Post-Stroke Rehabilitation: A Systematic Review. Sensors (Basel). 2023;23(3).

Jaqueline da Cunha M, Rech KD, Salazar AP, Pagnussat AS. Functional electrical stimulation of the peroneal nerve improves post-stroke gait speed when combined with physiotherapy. A systematic review and meta-analysis. Ann Phys Rehabil Med. 2021;64(1):101388.

Kundi MK, Spence NJ. Efficacy of mirror therapy on lower limb motor recovery, balance and gait in subacute and chronic stroke: A systematic review. Physiother Res Int. 2023;28(2):e1997.

Kim KH, Jang SH. Effects of Task-Specific Training after Cognitive Sensorimotor Exercise on Proprioception, Spasticity, and Gait Speed in Stroke Patients: A Randomized Controlled Study. Medicina (Kaunas). 2021;57(10).

Hyun SJ, Lee J, Lee BH. The Effects of Sit-to-Stand Training Combined with Real-Time Visual Feedback on Strength, Balance, Gait Ability, and Quality of Life in Patients with Stroke: A Randomized Controlled Trial. Int J Environ Res Public Health. 2021;18(22).

Bei N, Long D, Bei Z, Chen Y, Chen Z, Xing Z. Effect of Water Exercise Therapy on Lower Limb Function Rehabilitation in Hemiplegic Patients with the First Stroke. Altern Ther Health Med. 2023;29(7):429-33.

Moon Y, Bae Y. The effect of backward walking observational training on gait parameters and balance in chronic stroke: randomized controlled study. Eur J Phys Rehabil Med. 2022;58(1):9-15.

Lattouf NA, Tomb R, Assi A, Maynard L, Mesure S. Eccentric training effects for patients with post-stroke hemiparesis on strength and speed gait: A randomized controlled trial. NeuroRehabilitation. 2021;48(4):513-22.

Pérez-de la Cruz S. Comparison between Three Therapeutic Options for the Treatment of Balance and Gait in Stroke: A Randomized Controlled Trial. Int J Environ Res Public Health. 2021;18(2).

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Published

2025-09-08

How to Cite

1.
Mushtaq N, Hifsa Waheed, Fatima Tariq, Laiba Khalid Butt, Fizza Sabir, Alishah Malik, et al. COMPARATIVE EFFECTS OF ACTIVITY-BASED MIRROR TRAINING WITH OR WITHOUT RHYTHMIC AUDITORY STIMULATION TO IMPROVE LOWER EXTREMITY FUNCTIONS IN SUBACUTE STROKE PATIENTS: A RANDOMIZED CONTROLLED TRIAL. IJHR [Internet]. 2025 Sep. 8 [cited 2025 Sep. 25];3(5 (Health and Rehabilitation):78-86. Available from: https://insightsjhr.com/index.php/home/article/view/1316