QUALITY OF LIFE IN PEDIATRIC PATIENTS WITH ATOPIC DERMATITIS

Authors

  • Aisha Baloch Pakistan Institute of Medical Sciences, Islamabad, Pakistan Author
  • Mohammad Riaz Khan Pakistan Institute of Medical Sciences, Islamabad, Pakistan. Author
  • Mahvish Aftab Khan Pakistan Institute of Medical Sciences, Islamabad, Pakistan. Author
  • Amber Waqar Pakistan Institute of Medical Sciences, Islamabad, Pakistan Author

DOI:

https://doi.org/10.71000/6y8zxk20

Keywords:

Atopic Dermatitis, Quality of life, pediatrics

Abstract

Atopic dermatitis (AD) is one of the most prevalent chronic skin disorders in childhood and is associated with a significant impact on quality of life (QoL).

Objective: This study investigates QoL impairment among paediatric patients with AD using the Children’s Dermatology Life Quality Index (CDLQI).

Methodology: A total of 474 participants (mean age 14.1 ± 1.4 years; 56.5% male) were assessed. The mean CDLQI score was 9.6 ± 6.8, reflecting a moderate impairment.

Results: Severe impairment was reported by 35.6% and very severe impairment by 9.5% of patients.

Stratified analysis revealed that shorter duration of disease (<1 year), family history of atopy, urban environment, and exposure to allergens were significantly associated with worse QoL (p < 0.05). No significant differences were observed by gender or education level. These findings highlight the multifactorial burden of AD on children’s lives, underscoring the need for targeted interventions including environmental modifications, patient education, and psychosocial support.

Conclusion: By integrating quantitative data with clinical interpretation, this research contributes to the growing evidence base on the psychosocial dimensions of AD and provides a foundation for improved multidisciplinary care strategies in pediatrics.

Author Biographies

  • Aisha Baloch, Pakistan Institute of Medical Sciences, Islamabad, Pakistan

    Department of Dermatology, Pakistan Institute of Medical Sciences, Islamabad, Pakistan

  • Mohammad Riaz Khan, Pakistan Institute of Medical Sciences, Islamabad, Pakistan.

    Assistant Professor, Department of Dermatology, Pakistan Institute of Medical Sciences, Islamabad, Pakistan.

  • Mahvish Aftab Khan, Pakistan Institute of Medical Sciences, Islamabad, Pakistan.

    Assistant Professor, Department of Dermatology, Pakistan Institute of Medical Sciences, Islamabad, Pakistan.

  • Amber Waqar, Pakistan Institute of Medical Sciences, Islamabad, Pakistan

    Department of Dermatology, Pakistan Institute of Medical Sciences, Islamabad, Pakistan

References

Beattie, P. E., & Lewis-Jones, M. S. (2006). A comparative study of impairment of quality of life in children with skin disease and children with other chronic childhood diseases. British Journal of Dermatology, 155(1), 145-151.

Chamlin, S. L., Frieden, I. J., Williams, M. L., & Chren, M. M. (2004). Effects of atopic dermatitis on young American children and their families. Pediatrics, 114(3), 607-611.

Hon, K. L., Leung, T. F., Wong, K. Y., Chow, C. M., Ng, P. C., & Lam, M. C. (2005). Quality of life and psychosocial issues are important outcome measures in atopic dermatitis. Journal of Dermatological Treatment, 16(2), 83-87.

Lewis-Jones, M. S., & Finlay, A. Y. (1995). The Children's Dermatology Life Quality Index (CDLQI): initial validation and practical use. British Journal of Dermatology, 132(6), 942-949.

Nutten, S. (2015). Atopic dermatitis: global epidemiology and risk factors. Annals of Nutrition and Metabolism, 66(Suppl. 1), 8-16.

Odhiambo, J. A., Williams, H. C., Clayton, T. O., Robertson, C. F., & Asher, M. I. (2009). Global variations in prevalence of eczema symptoms in children from ISAAC Phase Three. Journal of Allergy and Clinical Immunology, 124(6), 1251-1258.

Silverberg, J. I. (2017). Public health burden and epidemiology of atopic dermatitis. Dermatologic Clinics, 35(3), 283-289.

Kim, J. P., Chao, L. X., Simpson, E. L., & Silverberg, J. I. (2016). Persistence of atopic dermatitis (AD): a systematic review and meta-analysis. Journal of the American Academy of Dermatology, 75(4), 681-687.

Deckers, I. A., McLean, S., Linssen, S., Mommers, M., van Schayck, C. P., & Sheikh, A. (2012). Investigating international time trends in the incidence and prevalence of atopic eczema 1990–2010: a systematic review of epidemiological studies. PLoS One, 7(7), e39803.

Weidinger, S., & Novak, N. (2016). Atopic dermatitis. The Lancet, 387(10023), 1109-1122.

Paller, A. S., & Mancini, A. J. (2015). Hurwitz Clinical Pediatric Dermatology: A Textbook of Skin Disorders of Childhood and Adolescence. Elsevier Health Sciences.

Charman, C. R., Morris, A. D., Williams, H. C. (2000). Topical corticosteroid phobia in patients with atopic eczema. British Journal of Dermatology, 142(5), 931-936.

Eckert, L., Gupta, S., Amand, C., Gadkari, A., & Mahajan, P. (2017). Impact of atopic dermatitis on health-related quality of life and productivity in adults in the United States. Journal of Investigative Dermatology, 137(6), 1362-1370.

Carroll, C. L., Balkrishnan, R., Feldman, S. R., Fleischer, A. B., & Manuel, J. C. (2005). The burden of atopic dermatitis: impact on the patient, family, and society. Pediatric Dermatology, 22(3), 192-199.

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Published

2025-07-18

How to Cite

1.
Baloch A, Mohammad Riaz Khan, Mahvish Aftab Khan, Amber Waqar. QUALITY OF LIFE IN PEDIATRIC PATIENTS WITH ATOPIC DERMATITIS. IJHR [Internet]. 2025 Jul. 18 [cited 2025 Aug. 28];3(4 (Health and Rehabilitation):711-9. Available from: https://insightsjhr.com/index.php/home/article/view/1275