FREQUENCY OF NECROTIZING ENTEROCOLITIS IN EARLY VERSES LATE TROPHIC FEEDING IN VLBW (VERY LOW BIRTH WIGHT) PRETERM INFANTS.
DOI:
https://doi.org/10.71000/4qzznb34Keywords:
Preterm infants, very low birth weight, early trophic feeding, necrotizing enterocolitis.Abstract
BACKGROUND: Because the gastrointestinal tract is immature, feeding (very low birth weight) VLBW or very preterm infants presents a special problem. Improving optimal growth, long-term results, and reducing morbidities all depend on early nutrition.
OBJECTIVE: To assess the frequency of necrotizing enterocolitis with early trophic feeding in very low birth weight preterm infant.
STUDY DESIGN: Descriptive vase study.
SETTING: Pediatrics Department, Sir Gangs Ram Hospital, Lahore.
DURATION OF STUDY: 6 months
METHODOLOGY: A total of 90 infants fulfilling selection criteria were included in the study. Demographic information (name, gender, gestational age at birth, birth weight) was obtained. Then infant was given early feed within 24 hours after birth. The choice of milk was of mother's milk. Then infants were followed-up in NUCI for next 24 hours. On the first day of feeding infant received 1- 2cc/kg of milk every 2-3hr and then the volume is set up of feed according to given feeding schedule table in succeeding days. Infant could be shift to oral feed when able to suck effectively. Daily feeding chart was maintained in each subject file. These infants were observed daily for 15 days in OPD. Parents were given feeding pattern. After 15 days, if infant showed NEC signs, then NEC was labeled. Infants with NEC were managed as per hospital protocol.
DATA ANALYSIS: Data was entered and analysed using SPSS version 20.
RESULTS: In our study, out of 90 cases, 48.88%(n=44) had <34 weeks of gestation whereas 51.12%(n=46) had >34 weeks of gestation, mean+sd was calculated as 33.09+1.88 weeks. Mean birth weight was calculated as 1306.67+129.95 grams, 35.56%(n=32) were male and 64.44%(n=58) were females. Frequency of necrotizing enterocolitis with early trophic feeding in very low birth weight preterm infant was recorded as 5.56%(n=5). CONCLUSION: The conclusion was the frequency of necrotizing enterocolitis with early trophic feeding is not very higher in very low birth weight preterm infant resulting in better neurodevelopmental and growth outcomes, which could lessen the social and financial burden that preterm places on society. However, the occurrence of NEC may be in mind of the pediatricians and parents as well.
References
Morgan J, Bombell S, McGuire W. Early trophic feeding versus enteral fasting for very preterm or very low birth weight infants. 2013.
Rusconi B, Warner BB. The Hidden Treasure of Neonatal Screening: Identifying New Risk Factors and Possible Mechanisms of Necrotizing Enterocolitis Through Big Data. The Journal of pediatrics 2017;181:9.
Hague KN. Necrotizing enterocolitis - Some things old and some things new: A comprehensive review. Journal of Clinical Neonatology 2016; 5(2):79-90.
Hague KN. Necrotizing enterocolitis-Some things old and some things new: A comprehensive review. Journal of Clinical Neonatology 2016;5(2):79.
Meinzen-Derr J, Poindexter B, Wrage L, Morrow A, Stoll B, Donovan! E. Role of human milk in extremely low birth weight infants risk of necrotizing enterocolitis or death. Journal of Perinatology 2009;29:57-62.
Syed Sajid Hussain Shah MS, Tahir Mehmood, Tausif Ahmed. Frequency and outcome of necrotizing enterocolitis in preterm neonates. J Ayub Med Coll Abbottabad 2015;27(1).
Institute of Medicine. Leading health indicators for healthy people 2020: letter report. Washington (DC): National Academies Press; 2011.
Blencowe H, Cousens S, Oestergaard MZ, Chou D, Moller AB, Narwal R, et al. National, regional, and worldwide estimates of preterm birth rates in the year 2010 with time trends since 1990 for selected countries: a systematic analysis and implications. Lancet 2012;379(9832):2162e72.
Matthews TJ, MacDorman MF, Thoma ME. Infant mortality statistics from the 2013 period linked birth/infant death data set. National vital statistics reports, 64. Hyattsville, MD: National Center for Health Statistics; 2015. p. 1e30.
McIntire DD, Leveno KJ. Neonatal mortality and morbidity rates in late preterm births compared with births at term. Obstet Gynecol 2008;111:35e41
Hamilton BE, Martin JA, Ventura SJ. Births: preliminary data for 2012. Natl Vital Stat Rep. 2013;62(3):1-20.
Thompson AM, Bizzarro MJ. Necrotizing enterocolitis in newborns: pathogenesis, prevention and management, Drugs 2008;68 (9):1227–38.
Group E. Incidence of and risk factors for neonatal morbidity after active perinatal care: extremely preterm infants study in Sweden (EXPRESS), Acta Paediatr 2010;99 (7):978–92.
Fitzgibbons SC, Ching Y, Yu D. Mortality of necrotizing enterocolitis expressed by birth weight categories. J Pediatr Surg 2009;44(6):1072–5
Neu J, Walker WA. Necrotizing enterocolitis. N Engl J Med 2011; 364(3):255–64.
Leaf A, Dorling J, Kempley S, McCormick K, Mannix P, Linsell L, et al. Early or Delayed Enteral Feeding for Preterm Growth-Restricted Infants: A Randomized Trial. Pediatrics 2012;129(5).
Sinha R, Venkatnarayan K, Dalal S, John B, Syed VS. To study the effect of early versus late trophic feeding in preterm neonates with mild respiratory distress syndrome. Indian Journal of Child Health 2017;4(1):27-30.
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